Dr Stephen M Kiwuwa

Dr.Kiwuwa Steven MpunguMB.Ch.B, Msc. PhDis a lecturer in the department of child Health and development centre with a specialization in Clinical Epidemiology and Biostatistics including Bioethics at Makerere University College of Health Sciences. He is interested in feasibility and community effectiveness of innovative intervention packages for maternal and new-born health in Uganda. More specifically he has over 8years’ experience in disease control, epidemiology research and graduate training at university level and over 20years’ experience in delivery of health care services at all levels of the health care system. He was formally the Regional contact point for the East African region FP7 project - The “Contact point network to attract  young African scientists to participate in EU funded research programs on poverty related diseases”(2007-2010). Furthermore he is skilled in program design, evaluation and monitoring with 7 years’ experience in research administration and ethics in human subjects research. He has a wealth of experience in Field epidemiological studies through international collaboration initiatives. Previous projects undertaken include: WORLD HEALTH ORGANISATION TDR RESEARCH CAPABILITY STRENGTHENING GRANT 14/09/2000 - 14/09 2005. Co-investigator of project Community malaria in pregnancy interventions as a pathfinder of better antenatal care utilization. MIM/TDR malaria related control interventions - 06/2005-06/2008(completed) in Luwero District. Co-investigator AMANET capacity strengthening grant for malaria vaccine trials  2007-october 2010 (completed). Dr. Kiwuwa was also a review team member for the evaluation of the early phase of implementation of the integrated community case management of malaria, pneumonia and diarrhea (2010-2013) in 34 districts of Uganda (WHO Uganda & UNICEF).

My research interests include community maternal and child health interventions, plasmodium falciparum immunogenicity and drug resistance markers, epidemiological surveillance for epidemic prone and emerging infectious diseases. In the area of Bioethics, my future research will focus on IRB performance issues, HIV disclosure ethics, ethics of genetic research, online ethics research and consent issues in diverse settings.

The results from this research are expected to provide evidence on the effectiveness of new strategies and interventions to improve maternal and newborn health and will contribute directly to the WHO Millennium Development Goals( MDGs) 5 (maternal health) and 4 (child health) and as about one third of all under-five mortality is related to perinatal causes. My key collaborators include researchers from Karolinskainstitutet,Johns Hopkins University and locally policy makers from the Ministry of Health and officials from the District directorates of health services and various Health units within Uganda.

PUBLICATIONS:

Kiwuwa MS, Charles K, Harriet MK. Patient and health service delay in pulmonary tuberculosis patients attending a referral hospital: a cross-sectional study. BMC Public Health. 2005 Nov 24;5:122.

Nakimuli-Mpungu E, Musisi S, Mpungu SK, Katabira E. Primary mania versus HIV-related secondary mania in Uganda. Am J Psychiatry. 2006 Aug; 163(8):1349-54; quiz 1480.

Nakimuli-Mpungu E, Musisi S, Mpungu SK, Katabira E The Clinical presentation of Bipolar disorder Mania in HIV positive patients in Uganda. Psychomatics 2009:50; 325-330.

Kiwuwa SM, Mufubenga. Use of antenatal care, maternity services, intermittent presumptive treatment and insecticide treated bed nets by pregnant women in Luwero district, UgandaMalaria  journal7:44 2008.

Sangaré LR, Stergachis A, Brentlinger PE, Richardson BA, Staedke SG, et al. 2010 Determinants of Use of Intermittent Preventive Treatment of Malaria in Pregnancy: Jinja, Uganda. PLoS ONE 5(11): e15066. doi:10.1371/journal.pone.0015066

Nakimuli-Mpungu.E , Mutamba Brian, Nshemerirwe S, Kiwuwa MS, Seggane Musisi. Effect of HIV infection on time to recovery from an acute manic episode. HIV/AIDS - Research and Palliative Care 2010:2 185–189.

Sangaré LR, Weiss NS, Brentlinger PE, Richardson BA, Staedke SG, Kiwuwa MS, Stergachis A. Patterns of anti-malarial drug treatment among pregnant women in Uganda. Malar J. 2011; 10:152.

Kiguba R, Kutyabami P, Kiwuwa S, Katabira E, Sewankambo NK. Assessing the quality of informed consent in a resource-limited setting: a cross-sectional study. BMC Med Ethics. 2012 Aug 21;13:21.

Kamugisha, E., Bujila, I., Lahdo, M., Pello-Esso, S., Minde, M., Kongola, G., Naiwumbwe, H., Kiwuwa, S.,Kaddumukasa, M., Kironde, F., Swedberg, G., Large differences in prevalence of pfcrt and pfmdr1 mutations between Mwanza, Tanzania and Iganga, Uganda-a reflection of differences in policies regarding withdrawal of chloroquine?  Acta Trop.121, 148-151. 2012

Kiwuwa MS, Byarugaba J, Wahlgren M, Kironde F. Detection of copy number variation and single nucleotide polymorphisms in genes involved in drug resistance and other phenotypic traits in P. falciparum clinical isolatescollected from Uganda. Acta Trop. 2012 Dec 7.

Mukisa Robert, Ddumba Edward, MusisiSeggane, MpunguKiwuwa Steven. Prevalence and types of cognitive impairment among patients with stroke attending a referral Hospital in Uganda.  African Journal of Neurological Sciences 2011 vol. 30, No. 2.

DavideAngeletti, Mpungu Steven Kiwuwa, Justus Byarugaba, Fred Kironde, and Mats Wahlgren. Short Report: Elevated Levels of High-Mobility Group Box-1 (HMGB1) in Patients with Severe or Uncomplicated Plasmodium falciparum Malaria.      Am. J. Trop. Med. Hyg., 2013.

Fred Kironde, Musa Sekikubo, Halima Naiwumbwe, FatumaNamusoke,  William Buwembo1, Steven Kiwuwa Brenda Oketch, Ramadhani Noor,  Roma Chilengi, Edison Mworozi, Mark Kaddumukasa. Hematology and blood serum chemistry reference intervals for children in Iganga district of Uganda. Health Vol.5, No.8, 1261-1267 (2013) http://dx.doi.org/10.4236/health.2013.58171

Catherine Kansiime, Stephen M Kiwuwa, Mugenyi Levi, Benon B Asiimwe, Achilles Katamba. Health service delay among pulmonary tuberculosis patients presenting to a National Referral Hospital, Kampala, Uganda: a Cross sectional study. The Pan African Medical Journal. 2013; 15:84

Factors associated with utilization of insecticide-treated nets in children seeking health care at a Ugandan hospital: perspective of child caregivers. Nankinga Z, Muliira JK, Kalyango J, Nankabirwa J, Kiwuwa S, Njama-Meya D, Karamagi C. J Community Health. 2012 Oct; 37(5):1006-14. doi: 10.1007/s10900-012-9546-z.