Dr. Aggrey Dhabangi (MB ChB), M.Med Paediatrics and Child Health ), PhD (Cand.)
Aggrey Dhabangi is a Lecturer at the Child Health and Development centre (CHDC), School of Medicine, Makerere University, and currently a PhD candidate at University of Amsterdam. At CHDC, he teaches undergraduate medical students; clinical Paediatrics (4th and 5th years), community research projects development and implementation (3rd year) and research methods and community diagnosis (2nd year) and well as supervision of medical students at community site placements.
Currently, he is the Ugandan trial co-coordinator of a three year study entitled; Malaria chemoprevention with monthly treatment with dihydroartemisinin-piperaquine for the post-discharge management of severe anaemia in children aged less that 5 years in Uganda and Kenya: a 3-year, multi-centre, parallel-group, two-arm randomized placebo controlled superiority trial.
He has also participated in various research projects at CHDC both qualitative and Quantitative including a survey of gender attitudes among young people in Uganda, a formative research for the Introduction of Typhoid vaccination and “WASH” interventions in Kasese district -Uganda, client satisfaction with Health services in Uganda, an assessment of the feasibility of two alternative strategies for delivering a full course of the Human Papilloma Virus (HPV) vaccine to girls in and out of schools in Uganda, among others.
His other prior research experiences include; was a local lead principal investigator of two year clinical trial - an R21 NIH-funded project entitled “Transfusion in Malaria” (HL 109518 01A1); based at the Acute care unit, Mulago hospital, Uganda. (NCT01586923), worked as a study physician for the Cytoadherence in Paediatric Malaria project; a 2 year observational Case – control malaria study performed at the Mulago Hospital Acute Care Unit and a 2 years experience in research, treatment and care for HIV/AIDS infected children including antiretroviral therapy at the Paediatric Infectious Diseases Institute (PIDC), Mulago.
His research interests include, but not limited to; Blood transfusion therapy, Childhood severe anemia, malaria, Early Childhood Development (ECD) and paediatrics HIV/AIDS.
B) PEER-REVIEWED PUBLICATIONS:
Dzik WS, Kyeyune D, Otekat G, Natukunda B, Hume H, Kasirye PG, Ddungu H, Kajja I, Dhabangi A, Mugyenyi GR, Seguin C, Barnes L, Delaney M. Transfusion Medicine in Sub-Saharan Africa: Conference Summary. Transfus Med Rev. 2015 Jul;29 (3):195-204.
Dhabangi A, Ainomugisha B, Cserti-Gazdewich C, Stowell C, Dzik WS. Transfusion medicine illustrated: Cerebral oxygenation during transfusion for profound anemia. Transfusion. 2014 Nov; 54(11):2802.
Erdman LK, Petes C, Lu Z, Dhabangi A, Musoke C, Cserti-Gazdewich CM, Lee CG, Liles WC, Elias JA, Kain KC. Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case-control study of African children. Malar J. 2014 Jul 21; 13(1):279.
Kim H, Erdman LK, Lu Z, Serghides L, Zhong K, Dhabangi A, Musoke C, Gerard C, Cserti-Gazdewich C, Liles WC, Kain KC. Functional roles for C5a and C5aR but not C5L2 in the pathogenesis of human and experimental cerebral malaria. Infect Immun. 2014 Jan; 82(1):371-9.
Dhabangi A, Mworozi E, Lubega IR, Cserti-Gazdewich CM, Maganda A, Dzik WH. The effect of blood storage age on treatment of lactic acidosis by transfusion in children with severe malarial anaemia: a pilot, randomized, controlled trial. Malar J. 2013 Feb 6; 12:55.
Higgins SJ, Xing K, Kim H, Kain DC, Wang F, Dhabangi A, Musoke C, Cserti-Gazdewich CM, Tracey KJ, Kain KC, Liles WC. Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria. Malar J. 2013 Mar 19;12:105.
Cserti-Gazdewich CM, Dhabangi A, Musoke C, Ssewanyana I, Ddungu H, Nakiboneka-Ssenabulya D, Nabukeera-Barungi N, Mpimbaza A, Dzik WH. Inter-relationships of cardinal features and outcomes of symptomatic pediatric Plasmodium falciparum malaria in 1,933 children in Kampala, Uganda. Am J Trop Med Hyg. 2013 Apr; 88(4):747-56.
Cserti-Gazdewich CM, Dhabangi A, Musoke C, Ssewanyana I, Ddungu H, Nakiboneka-Ssenabulya D, Nabukeera-Barungi N, Mpimbaza A, Dzik WH. Cytoadherence in paediatric malaria: ABO blood group, CD36, and ICAM1 expression and severe Plasmodium falciparum infection. Br J Haematol.2012 Oct; 159(2):223-36.
Siu GE, Bakeera-Kitaka S, Kennedy CE, Dhabangi A, Kambugu A. HIV serostatus disclosure and lived experiences of adolescents at the Transition Clinic of the Infectious Diseases Clinic in Kampala, Uganda: a qualitative study. AIDS Care. 2012; 24(5):606-11.
S. Bakeera-Kitaka, A. Conesa-Botella, Dhabangi, A. Maganda, A. Kekitiinwa,R. Colebunders, D. R. Boulware. Tuberculosis in human immunodeficiency virus infected Ugandan children starting on antiretroviral therapy, int j tuberc lung dis 2011; 15(8):1082–1086.
Finney CA, Hawkes CA, Kain DC, Dhabangi A, Musoke C, Cserti-Gazdewich C, Oravecz T, Liles WC, Kain KC. S1P is associated with protection in human and experimental cerebral malaria. Mol Med. 2011; 17(7-8):717-25
Erdman LK, Dhabangi A, Musoke C, Conroy AL, Hawkes M, Higgins S, Rajwans N, Wolofsky KT, Streiner DL, Liles WC, Cserti-Gazdewich CM, Kain KC. Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study. PLoS One. 2011 Feb 25;6(2).
Cserti-Gazdewich CM, Dzik WH, Erdman L, Ssewanyana I, Dhabangi A, Musoke C, Kain KC. Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in Uganda. Malar J 2010; 9: 233.
Murphy S, Cserti-Gazdewich C, Dhabangi A, Musoke C, Nabukeera-Barungi N, Price D, King ME, Romero J, Noviski N, Dzik W. Ultrasound findings in Plasmodium falciparum malaria: a pilot study. Pediatr Crit Care Med. 2011 Mar; 12(2)
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